| Subject: |
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Re: A message from Brent Hoadley, PhD Part 2 |
| Name: |
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Claudia French RN, LPHA |
| Date Posted: |
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May 21, 07 - 2:48 PM |
| IP Address: |
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72.186.110.244 |
| Email: |
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cfrench180@tampabay.rr.com |
| Website: |
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http://imva.info/diabetes.shtml |
| Message: |
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Message from Brent Hoadley continued:
<(I’ve thought about this in terms of our medical professionals: Because they all have that M.D. firmly affixed behind their names, we “assume” that they are so well-educated, so intelligent that they ascend to the realm of “god-like.” In every graduating class, however, there is of course a NUMBER ONE—but there is also a 154th or 233rd . . . charmers who just eked out their title through perseverance, luck, charm, bribery . . . But the diploma hanging on the wall of the one who just managed to graduate clothes him in the same intellectual garment that dresses the top-of-the-class overachiever. Funny, isn’t it, how bothersome adjectives disappear and no longer qualify reality?)
The other document which I reviewed, and you all may want to obtain your own copy, is called “Galenics of Insulin,” by Jens Brange. Springer Verlog is the publisher. This covers insulin-- from 1922 through rDNA insulin (1983). A statement in the FOREWORD explains to all diabetics the present situation (and I paraphrase): “The therapeutic index (the ratio between a lethal and an effective therapeutic dose) is very low for insulin.” “Pharmaceutical formulations must recognize meal-bolus as well as basal requirements and this challenge is an on-going science.” Aren’t you all glad to be participants in an ongoing experiment? It was interesting to note the many variety of insulins available before 1982 (approximately 27) and it was further known that after improvements in purification that all natural insulins’ antigenecity was also reduced to the point that diabetics, in most cases, were NOT allergic. Probably the most important table in this publication appears on page 79. A Novo pork product was shown to be greater than 99% pure, while an E. coli-produced human insulin only exceeded the 97 percentile (a Lilly product). Both products were purified using HPLC. The fact human insulin had a greater impurity level would fly in the face of early studies which indicate that human insulin produced a lesser immunogenic response. Most recent studies regarding porcine and human insulin indicate that immunogenecity in great part is a response to impurities or other diluents, modifiers, etc. that are a component of produced insulin. What is even more interesting is to compare all this data to the information these companies supply to the U.S. patent office.
Some of the interesting things you may want to consider:
The rDNA process has opened up a whole field of analog research, providing opportunity for millions of potentially patentable human insulin analogs, including some not-so-human products.
It is important to know that any natural analog, including bovine and porcine insulin, COULD be made by rDNA technology. Please recognize this analog would not be patentable; it would offer comparison to the “human” insulin and other analogs; and most importantly, the pharmaceutical industry does not want comparisons made of these (natural) analogs with their present-day synthetic, laboratory-created insulin analogs. They don’t want to “ask the question” when the answer may be “the natural analog was best” or possibly “the rDNA insulins/analogs were NOT the problem—the process was.”
Most of us who know what diabusiness is doing to the diabetic community should tell all of our diabetic friends that CURE is the only solution. Please take note that Novo and Lilly both will be in the process of taking human insulin off the market when the patent expires. At the same time, they will be trying to prevent generic insulin makers from introducing these products into the U.S. because it is no longer made here. (Can you say “new NDA” and “bioequivalency”?) All of the “newbies” to diabetes will then need to start floundering with new treatment protocols as part of a Phase IV guinea-pig process. The long-term results of human insulin and its analogs would prove to be a nightmare if the right questions were asked, and the data properly collected. I think the medical community, our charities, and especially our pharmaceuticals have found a way to enslave an entire population base.
Brent Hoadley, Ph.D.
http://www.tooprofitabletocure.com
"Of all the forms of inequality, injustice in health care
is the most shocking and inhumane." --Martin Luther King Jr. >
I hope you will pass on this message to those who might need to know the truth. And thanks, Brent, for all that you do! Claudia |
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