Some interesting facts on Wikipedia about the House of Borgia:

Especially during the reign of Alexander VI, they were suspected of many crimes, including adultery, incest, simony, theft, bribery, and murder (especially murder by arsenic poisoning). Because of their grasping for power, they made enemies of the Medici, the Sforza, and the Dominican friar Girolamo Savonarola, among others. They were also patrons of the arts who contributed to the development of Renaissance art.

The Borgia family stands out in history as being infamously steeped in sin and immorality, yet there is evidence to suggest that this one-dimensional characterization is a result of undeserved contemporary critiques.